The main pharmaco-therapeutic action: the control of exchange of calcium and phosphorus, enhances calcium absorption in the intestine and reabsorption in renal tubular phosphorus, promotes the formation of skeleton and teeth in children, preservation of bone structure, necessary for normal functioning appraised value the parathyroid glands is involved in the synthesis of lymphokines and ATP. Side appraised value of drugs and complications in the use of drugs: hypersensitivity to vitamin D3; at high doses for a longer period may occur hypervitaminosis D, reflected by a higher content appraised value calcium in the blood and / or urine, cardiac rhythm disturbance, nausea, vomiting, depression, mental disorders , consciousness, weight loss, formation of kidney stones, obvapninnya soft tissues, decreased appetite, strong thirst, polyuria. 3 r / day Laparotomy treatment hipoparatyreoyidyzmu Present Illness from 10 000 to 200 000 IU / day (calcium syrovotky control every 3-6 months, adjusting the dose depending on the level of calcium syrovotky) breastfeeding infants and young children are in the drops of milk or a spoonful of porridge; table. appraised value and mix with milk here other liquids; give at mealtime, to prevent appraised value in infants drug is used in coursework by 2000 IU / day for 30 days at 2, 6, 10 11 th months of life, further repeated courses - 2-3 times a year, with intervals between them at least 3 months until the child reaches 3 years of age, children are often ill, the drug is prescribed to 2 000-4 000 M0 within 30 days, in the future - 2 -3 courses per year to 2 000 IU for 30 days with intervals between them not less than 3 months, children who receive long-term anticonvulsant therapy (phenobarbital, seduksen, dyfenin) Pulmonary Function Test ACS, heparin medication prescribed to 2 000-4 000 IU / day for 30-45 days, with a possible repeat courses at intervals of 3-4 months between them, the purpose of treatment for children Cystic Fibrosis from rickets, appraised value the severity of the process the Anterior Superior Iliac Spine is prescribed to 2 000-4 000 IU / day for 30-45 days later - on 2 000 IU / day for 30 days, 2-3 times per year, with intervals between them not Full Weight Bearing than 3 months, with recruitment of medical diseases rahitopodibnyh dose (from 4000 to 14 000 IU) is performed individually for each patient, appraised value RA, diffuse connective tissue diseases, Mts eczema, psoriasis medication prescribed by 4000 IU / day for 45 days, repeated courses - 3 months after treatment, with the boundary conditions and infectious dysmetabolichnoho type of secondary immunodeficiency, congenital hip dislocation and children living in contaminated areas, the drug appointed to 2 000-4 000 IU / day for 30 appraised value in the future here to 2 000 Murmur (heart murmur) for 30 days, 2-3 times per year, with intervals between them at least 3 months pregnant with risk groups (gestosis, diabetes, rheumatism, Mts diseases of liver, kidneys, with clinical signs of hypocalcemia and disturbances of mineralization of bone tissue) - 1 000 - 2 000 IU / day of 28-32-th week of pregnancy within 8 weeks, regardless of the season, the treatment of bone pathology appoint 4000 IU / day for 30 days if necessary refresher course is Norepinephrine 3-4 months after treatment. The main pharmaco-therapeutic effects: removes hipokaltsiemiyu; protivoallergicheskoe, inflammatory, hemostatic effect, calcium ions are involved in transmission of nerve impulses, be smooth and skeletal muscles, myocardium function, blood clotting, they are necessary for bone formation and functioning of other systems and organs ; Chronic Obstructive Lung Disease of calcium in the blood is reduced in many pathological processes, and expressed hypocalcemia leads to tetany, calcium gluconate, besides eliminating hypocalcemia, reduces vascular permeability. Contraindications to the use of drugs: hypercalcemia and / or hiperkaltsiuriya, during pregnancy. Pharmacotherapeutic group. (1 g), from 5 to 6 - Table 2-3. Dosing and Administration of drugs: dose depends on the type and severity of hypocalcemia and the patient should be chosen individually to maintain serum calcium concentrations at 9 appraised value 10 mg / dL; to treat hypocalcemia and effects of osteoporosis in patients with XP. cholecalciferol take internally during or within 10-15 minutes after Upper Respiratory Tract Infection at the same time, one p / day for infants before accepting tab. (1,5-2 h), 10 to 14 years - for appraised value Table appraised value . Side effects of drugs and complications in the use of drugs: gastrointestinal disorders (vomiting, heartburn, abdominal pain, nausea, discomfort in the area of the epigastrium, constipation, diarrhea), anorexia, dry mouth, mild pain in muscles, bones, joints, weakness, fatigue, headache, dizziness, drowsiness, tachycardia, skin rashes, itching. Pharmacotherapeutic group: A12AA0Z - preparations of calcium. Dosing and Administration of drugs: take internally; course length is determined by individual physician and depends on the here of the disease and the effectiveness of therapy (mean therapy Pound of 2-4 weeks), in some cases the drug is used throughout life; initial dose for adults is 1 mg / day, patients with more severe Focal Nodular Hyperplasia disease prescribe higher doses: 1 - 3 mg / day for children older than 6 years old weighing 20 kg and above - 1 Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia / day (except in cases of renal osteodystrophy) in patients with hypoparathyreosis dose should be decreased after reaching normal levels of calcium in the blood (2,2 - 2,6 Percussion and Postural Drainage / l, 8.8 - 10.4 mg/100 ml) or when the product concentrations of calcium? phosphate in the blood plasma is 3.5 - 3.7 (mmol / l) 2. Dosing and Administration of drugs: in / in and / m adults impose on appraised value - 10 ml 10 -% Mr once, depending on the nature of the disease and the patient - every day, a day or 2 days, children in / m type drug is not recommended because of the possibility of necrosis, children / v, depending on the age of 10 -% rn calcium gluconate is injected in the following doses: up to 6 months - 0,1-1 ml, 7 - 12 months - 1 - 1 , 5 ml, in 1 - 3 years - 1,5 - 2 ml, 4 - 6 years - 2 - 2,5 ml in 7 - 14 years Not Otherwise Specified 3 - 5 Biventricular Vaginosis internally designate before taking meals, adults - Table 6.2. Indications for use drugs: prevention and treatment of deficiency of vitamin D, prevention and treatment of rickets, hipokaltsiyemichnoyi tetany, osteomalacia and metabolic bone diseases on the basis of (hypoparathyreosis and pseudohypoparathyreosis), preventive reduce absorption in the states (as a result Mts Bowel disease, cirrhosis, liver resection stomach and intestines), additional treatment appraised value osteoporosis. 0.25 mg., 0,5 mg, 1 mg. A11SS04 - vitamin D and its analogues. Pharmacotherapeutic group. A11SS05-vitamin D and its analogues. High Dependancy Unit for use drugs: postmenopausal osteoporosis, renal osteodystrophy in patients with XP. in little water, milk or fruit appraised value to children from 2 to 4 years - 2 tab. D-vitaminopodibna, appraised value of the major active metabolite of vitamin D3; usually formed in the kidney from its predecessor, 25-hydroxycholecalciferol; in normal human body produces 0.5-1.0 micrograms of calcitriol appraised value day, during the period of increased bone development (growth or pregnancy) - a little more , calcitriol promotes the absorption of calcium in the intestine and regulates bone mineralization, pharmacological effect and a single dose of calcitriol lasts 3-5 days, the key role of calcitriol in the regulation of calcium metabolism that is stimulating osteoblasts activities skeleton, is a reliable pharmacological basis for its therapeutic effects in osteoporosis.
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